✳️ Aim

The SCICONX Journal of Stem Cells and Regenerative Medicine (JSCRM) aims to serve as a premier global platform for publishing transformative, high-quality research that advances our understanding of stem cell biology, regenerative healing processes, tissue engineering innovations, and emerging therapeutic technologies.

Our primary goal is to accelerate progress in both basic and translational science by connecting discovery-driven research with clinical applications that improve human health, repair damaged tissues, and restore organ function.

✦ JSCRM is committed to:

• Promoting scientific excellence and ethical research practices
• Highlighting groundbreaking strategies that push the boundaries of cellular therapies
• Facilitating global collaboration among scientists, clinicians, engineers, and biotechnology innovators
• Bridging the gap between bench side discoveries and bedside applications
• Supporting a multidisciplinary approach to solving complex biomedical challenges

The journal seeks to advance a future where regenerative therapies are standard, accessible, and transformative for patients worldwide.

✳️ Scope of the Journal

JSCRM publishes comprehensive, original, and cutting-edge research across the full spectrum of stem cell sciences and regenerative medicine. The journal welcomes manuscripts from foundational biology to clinical investigations, including technological advances driving next-generation therapeutic solutions.

Our scope encompasses, but is not limited to, the following thematic areas:

1. Stem Cell Biology & Mechanisms

• Embryonic, somatic, and induced pluripotent stem cells (iPSCs)
• Stem cell self-renewal, differentiation, and plasticity
• Cell signalling networks and molecular pathways
• Stem cell epigenetics and gene regulatory circuits
• Stem cell–microenvironment interactions (niche biology)

2. Regenerative Medicine & Tissue Repair

• Cellular therapies for tissue and organ regeneration
• Strategies to restore function after injury, aging, or disease
• Regenerative responses in musculoskeletal, neurological, cardiac, renal, hepatic, and endocrine systems
• Immunomodulation in regenerative healing
• Bioactive molecules, growth factors, and extracellular vesicles in tissue repair

3. Tissue Engineering & Biofabrication

• Engineered biomaterials and biocompatible scaffolds
• 3D bioprinting and organoid construction
• Artificial and lab-grown tissues
• Bioengineered organoids for modelling diseases
• Smart materials and nanotechnology for regeneration

4. Cellular Reprogramming & Gene-Based Therapies

• Reprogramming technologies for generating stem cell lines
• CRISPR and gene-editing approaches
• Genomic engineering for targeted regeneration
• Cell fate manipulation for therapeutic purposes
• Gene–cell combined therapies

5. Translational & Preclinical Studies

• Animal models of regeneration
• Preclinical testing of cellular and tissue therapy strategies
• Safety, efficacy, and biocompatibility assessments
• Validation of engineered tissues and functional recovery outcomes

6. Clinical Applications & Therapeutic Trials

• Clinical investigations on stem cell-based treatments
• Regenerative interventions in orthopaedics, cardiology, neurology, ophthalmology, and reconstructive medicine
• Cell transplantation, grafting, and regenerative rehabilitation
• Outcome-based analyses of stem cell therapies

7. Organoids, Lab-Grown Systems & Disease Modelling

• Organoid technology for mechanistic studies
• Bioengineered platforms for understanding disease
• Personalized medicine applications
• High-throughput screening with stem cell-derived models

8. Biomaterials & Regenerative Technologies

• Bioactive polymers, hydrogels, and nanocomposites
• Materials that mimic extracellular matrix (ECM) environments
• Controlled delivery systems for regenerative factors
• Hybrid materials integrating biology with engineering

9. Ethical, Regulatory & Industry Perspectives

• Ethical considerations surrounding stem cell research
• Guidelines for clinical translation and regulatory compliance
• Manufacturing standards for therapeutic-grade cell products
• Commercialization strategies and biotech innovation paths

✦ What We Aim to Achieve Through Our Scope

Through this diverse yet focused scope, JSCRM intends to:

• Enable cross-disciplinary knowledge exchange
• Promote innovations that accelerate regenerative breakthroughs
• Support clinical translation and evidence-based therapies
• Encourage transformative solutions for global health challenges
• Build a central, trusted resource for the international research community

✦ Who Should Contribute?

The journal invites submissions from:

• Stem cell biologists
• Regenerative medicine researchers
• Tissue engineers
• Biomedical scientists
• Geneticists and molecular biologists
• Clinical researchers and surgeon-scientists
• Pharmaceutical and biotech R&D teams
• Biomedical engineers and biomaterials experts
• Translational medicine specialists
• Early-career researchers and postdoctoral scientists

The SCICONX Journal of Stem Cells and Regenerative Medicine exist to foster pioneering ideas, translate scientific insights into clinical realities, and shape a future where regenerative therapies restore life, function, and hope for patients worldwide. We welcome your most innovative, rigorous, and impactful contributions.