✦ Aims

The SCICONX Journal of Immunobiology aims to serve as a dynamic and authoritative platform for advancing the understanding of the immune system across diverse biological, clinical, and technological dimensions. The journal’s primary objectives are:

1. To Promote High-Quality Immunobiology Research

We aim to publish rigorous, peer-reviewed studies that deepen the molecular, cellular, and systemic understanding of immune processes in health and disease.

2. To Bridge Basic and Translational Immunology

Our goal is to highlight the continuum from foundational immunological discoveries to clinically relevant solutions, including novel diagnostics, immunotherapies, and vaccine technologies.

3. To Support Interdisciplinary Approaches

We encourage research that integrates immunology with genetics, microbiology, oncology, computational biology, systems biology, and biomedical engineering.

4. To Advance Global Health Through Immunological Innovation

The journal seeks to disseminate discoveries that impact global disease management, immune-mediated disorders, infectious diseases, and emerging biological threats.

5. To Foster Scientific Integrity and Open Access Knowledge

Through our open-access publishing model, we aim to democratize access to cutting-edge immunobiology research and promote transparency, reproducibility, and ethical scientific communication.

✦ Scope

The scope of SCICONX Journal of Immunobiology covers a broad and evolving spectrum of topics related to immune system development, function, dysfunction, and therapeutic manipulation. The journal welcomes high-impact contributions in the following core areas:

1. Molecular & Cellular Immunology

• Mechanisms of innate and adaptive immunity
• Immune cell development, signaling, and homeostasis
• Molecular regulators of inflammation
• Antigen processing and presentation
• Crosstalk between immune cells, tissues, and organ systems

2. Host–Pathogen Interactions

• Immune responses to bacteria, viruses, fungi, and parasites
• Pathogen immune evasion strategies
• Molecular determinants of infection immunity
• Emerging and re-emerging infectious diseases

3. Immunogenetics & Immunoregulation

• Genetic and epigenetic control of immune responses
• Autoimmunity and immune tolerance
• HLA biology and population immunogenomics
• Regulation of cytokines, chemokines, and signaling pathways

4. Tumor Immunology & Immuno-Oncology

• Mechanisms of tumor immune surveillance
• CAR-T cells and engineered immune cells
• Checkpoint blockade and immunomodulatory therapies
• Tumor microenvironment dynamics
• Predictive biomarkers in cancer immunotherapy

5. Clinical & Translational Immunology

• Immune-mediated diseases (autoimmune, allergic, inflammatory)
• Transplantation immunobiology
• Immune dysfunction in metabolic, cardiovascular, and neurological diseases
• Therapies targeting immune checkpoints, cytokines, or cellular functions

6. Vaccines & Immunotherapeutics

• Vaccine design, adjuvants, and delivery systems
• Next-generation platforms (mRNA, DNA, viral vectors, nanoparticle vaccines)
• Immune memory and hyperactivation
• Evaluation of vaccine efficacy and correlates of protection

7. Systems, Computational & Structural Immunology

• Immunomics, multi-omics integration, and network modeling
• AI/ML-driven immune system predictions
• Structural insights into immune receptors and ligands
• Computational approaches for vaccine and therapeutic development

8. Microbiome–Immune System Interactions

• Influence of gut, skin, and mucosal microbiota on immunity
• Microbial metabolites and immune modulation
• Dysbiosis and immune disorders
• Host–microbiome crosstalk in infection and chronic diseases

9. Environmental, Chemical & Nutritional Immunobiology

• Immune impacts of pollutants and environmental exposures
• Immunotoxicology and safety assessments
• Nutritional immunology and metabolic regulation
• Climate change effects on immune health

10. Emerging Topics

The journal is especially interested in cutting-edge domains such as:

• Synthetic immunology and bioengineered immunity
• Nanotechnology in immunotherapy
• Immune system aging (immunosenescence)
• Personalized immunology and precision medicine
• Gene editing (CRISPR-based immune modulation)

✦ Article Types Accepted

• Original Research Articles
• Review Articles & Mini Reviews
• Short Communications
• Clinical Studies
• Case Reports (selective)
• Data Papers, Immunomics Reports
• Technical Notes & Methodology Papers
• Commentaries, Perspectives, and Hypothesis Articles
• Special Issue Articles

✦ Who Should Submit?

The journal welcomes contributions from:

• Immunologists
• Clinical scientists
• Microbiologists and virologists
• Oncologists and cancer researchers
• Geneticists and molecular biologists
• Vaccine scientists and immunotherapists
• Computational and systems biologists
• Biomedical engineers and biotechnologists

Through its wide-ranging scope and commitment to scientific excellence, SCICONX Journal of Immunobiology aims to become a premier destination for next-generation immunology research. By bridging foundational insights with modern therapeutic advances, the journal supports the global scientific community in shaping the future of immune-based science and medicine.