Predictive Value of Triglyceride-Glucose Index for Left Ventricular Hypertrophy in Hypertensive Patients
Ning Zhang 1 , Congying Wang 2 , Kangkang Su 3 *,Abstract
Insulin Opposition (IR) is a significant affecting element in the pathogenesis of Left Ventricular Hypertrophy (LVH) in patients with hypertension. Fatty substance Glucose (TyG) record is a straightforward mark of IR. Notwithstanding, the proof on the relationship between TyG record and LVH is restricted. Clinical information of 440 hypertensive patients were reflectively gathered and isolated into two gatherings as indicated by Left Ventricular Mass file (LVMI): LVH bunch (LVMI ≥ 115 g/m2 (men) or ≥ 95 g/m2 (ladies), n=94), non-LVH bunch (LVMI<115 g/m2 (men) or <95 g/m2 (ladies), n=346), and TyG record was determined in view of Fasting Plasma Glucose (FPG) and fatty substances (TG) levels. The distinction in TyG file between two gatherings was genuinely critical (p=0.012). Connection investigation showed that LVMI was decidedly corresponded with TyG file (r=0.406, p<0.001). Multivariate strategic relapse examination results uncovered that orientation (OR=5.95, 95% CI: 2.565-13.8，p<0.001) and TyG file (OR=5.155，95% CI: 1.304-20.38，p=0.019) were free affecting elements for the event of LVH in hypertensive patients. The region under the bend (AUC) for TyG file to anticipate LVH in hypertensive patients was 0.591 (95% CI: 0.526-0.656). The AUC for TyG record to anticipate LVH in male and female hypertensive patients was 0.704 (95% CI: 0.593-0.816) and 0.637 (95% CI: 0.556-0.719), separately. TyG file is a free impacting factor for LVH in hypertensive patients, and unquestionably somewhat influences myocardial rebuilding in hypertensive patients. TyG file has a higher prescient incentive for LVH in male hypertensive patients.
Introduction
The quantity of individuals with hypertension overall was around 1.13 billion out of 2015, and the commonness of hypertension in grown-ups was around 30%-45%. With the further extension of the maturing populace and the increment of undesirable ways of life like high-fat eating routine, smoking, stationary, and keeping awake until late, the quantity of hypertensive patients will keep on expanding overall [1]. Hypertension, as one of the most widely recognized constant sicknesses around the world, requires our consideration. Left Ventricular Hypertrophy (LVH) is one of the normal subclinical objective organ harms brought about by hypertension, which can essentially expand the gamble of coronary atherosclerotic coronary illness, cardiovascular breakdown, stroke and, surprisingly, unexpected demise in hypertensive patients [2,3].
RESULTS
Gauge information of the two gatherings of patients: As indicated by the consideration and avoidance rules, 440 patients were eventually included (Table 1), including 239 guys and 201 females, with a typical period of 53.99±13.93 years old. There were 94 cases in the LVH bunch and 346 cases in the non-LVH bunch, and the rate of LVH in hospitalized hypertensive patients was 27.2%. The commonness of LVH in female hypertensive patients was 34.3%, and the pervasiveness of LVH in male hypertensive patients was 10.5%. There were genuinely tremendous contrasts between the two gatherings as far as orientation, smoking history, age, SBP, beat pressure, serum creatinine, uric corrosive , TG, and TyG file (all p<0.05); there was no measurably huge distinction in course of hypertension, DBP, pulse, BMI, FPG, eGFR, TC, HDL-C, and LDL-C between the two gatherings (all p>0.05).
Author Info
1 Department of Science and Technology, North China University of Science and Technology, Tangshan, China2 Department of Life Science, Jiangsu Normal University, Xuzhou, Jiangsu 221116, China
3 Department of Heart Center, Hebei General Hospital, Shijiazhuang, China
Received: 27-Jun-2025, Manuscript No. JCEC-23-27775; Editor assigned: 30-Jun-2025, Pre QC No. JCEC-23-27775 (PQ); Reviewed: 14-Jul-2025, QC No. JCEC-23-27775; Revised: 22-Jul-2025, Manuscript No. JCEC-23-27775 (R); Published: 31-Jul-2025
Citation: Zhang N, Lan J, Wang C, Jin Z, Su K, Shuxia Chen S, et al. (2025) Predictive Value of Triglyceride-Glucose Index for Left Ventricular Hypertrophy in Hypertensive Patients. J Clin Exp Cardiolog. 16:936.
Copyright: © 2025 Zhang N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
