✦ Aim

The Journal of Medicinal Chemistry aims to serve as a premier international forum for the dissemination of cutting-edge research and scholarly discussion in the field of medicinal chemistry. Our central objective is to promote the advancement of knowledge in drug discovery, molecular design, and chemical biology, while highlighting the vital role that chemistry plays in improving therapeutic outcomes and human health.

The journal is committed to publishing high-quality, peer-reviewed articles that not only present novel findings but also provide conceptual and methodological insights. We encourage contributions that foster interdisciplinary collaboration, connect fundamental chemistry with biological relevance, and accelerate the transition from laboratory research to clinical application.

✦ Scope

The Journal of Medicinal Chemistry covers a comprehensive spectrum of research areas that reflect the evolving landscape of drug discovery and development. The journal invites original research articles, reviews, mini-reviews, perspectives, and short communications in (but not limited to) the following domains:

• Drug Design & Development
  • Rational drug design, molecular docking, and target-based approaches
  • Fragment-based, ligand-based, and structure-guided drug discovery
  • Multitarget drug design and polypharmacology strategies
• Synthetic & Natural Products Chemistry
  • Design, synthesis, and optimization of bioactive molecules
  • Development of chemical libraries and diversity-oriented synthesis
  • Discovery of bioactive compounds from natural sources and their modifications
• Computational & Theoretical Medicinal Chemistry
  • Quantitative structure–activity relationship (QSAR) studies
  • Molecular dynamics simulations and computational modeling
  • Artificial intelligence and machine learning applications in drug discovery
• Chemical Biology & Pharmacology
  • Mechanistic studies of drug–target interactions
  • Biochemical and pharmacological evaluation of novel compounds
  • Medicinal chemistry of peptides, nucleotides, and biomacromolecules
• Translational & Applied Medicinal Chemistry
  • Pharmacokinetics, metabolism, and toxicity studies
  • Medicinal chemistry aspects of nanomedicine and drug delivery systems
  • Development of chemical probes and diagnostic agents

✨ Commitment to Interdisciplinary Excellence

The Journal of Medicinal Chemistry embraces the interdisciplinary nature of modern drug discovery, encouraging submissions from researchers in chemistry, biology, pharmacology, bioinformatics, nanotechnology, and allied fields. By fostering cross-disciplinary dialogue, the journal aims to accelerate the development of safe, effective, and innovative therapeutics.

Our ultimate vision is to provide a dynamic platform where scientific creativity meets translational relevance, ensuring that medicinal chemistry continues to contribute meaningfully to global health challenges.