✦ Aim of the Journal

The SCICONX Journal of Cellular Immunology and Tissue Engineering (JCITE) aims to serve as a dedicated scholarly platform for advancing knowledge at the intersection of immune biology, cellular science, and tissue engineering. The journal is committed to publishing rigorous, innovative, and ethically conducted research that deepens the understanding of how immune systems interact with cells, biomaterials, and engineered tissues in both physiological and pathological contexts.

JCITE seeks to foster interdisciplinary dialogue between immunologists, tissue engineers, biomaterials scientists, clinicians, and translational researchers, with the ultimate goal of accelerating the development of safe, effective, and immune-compatible regenerative therapies.

✦ Scope of the Journal

The scope of JCITE encompasses fundamental, translational, and applied research that explores immune–cell–tissue interactions across multiple biological scales, from molecular signalling pathways to whole-tissue and organ-level responses. The journal welcomes original contributions that address both mechanistic insights and practical applications relevant to regenerative medicine and biomedical engineering.

✦ Core Thematic Areas

JCITE publishes research in the following core areas, without being limited to them:

1. Cellular and Molecular Immunology

• Immune cell signalling, activation, and differentiation
• Cytokine networks and immune regulatory pathways
• Innate and adaptive immune responses in tissue environments
• Immune surveillance, tolerance, and immune memory in regeneration

2. Immune Regulation in Tissue Engineering

• Immune-mediated integration of engineered tissues
• Host responses to implanted biomaterials and scaffolds
• Foreign body reactions and immune compatibility strategies
• Immunological challenges in tissue grafting and transplantation

3. Stem Cells, Progenitor Cells, and Immunity

• Immune modulation of stem cell fate and function
• Immunogenicity of stem cell–derived constructs
• Stem cell–immune cell crosstalk in tissue repair
• Cellular therapies and immune safety considerations

4. Biomaterials and Immuno-engineering

• Design of immunomodulatory biomaterials
• Surface chemistry and immune cell interactions
• Immune-responsive and bioactive scaffolds
• Immuno-engineering approaches for controlled tissue regeneration

5. Tissue Repair, Remodelling, and Regeneration

• Inflammation and resolution in wound healing
• Fibrosis, scarring, and chronic immune activation
• Vascularization and immune involvement in tissue maturation
• Tissue remodelling in health and disease

6. Advanced Cell and Tissue Models

• 3D culture systems and organoid technologies
• Immune-integrated tissue models
• Micro-physiological systems and immune-on-chip platforms
• In vitro modelling of immune–tissue interactions

7. Translational and Clinical Research

• Preclinical studies of immune-compatible tissue constructs
• Clinical evaluation of regenerative and cell-based therapies
• Immunological biomarkers in tissue engineering outcomes
• Regulatory and safety considerations in clinical translation

✦ Interdisciplinary Emphasis

JCITE strongly encourages submissions that bridge traditionally separate disciplines. Studies integrating biology, engineering, materials science, computational modelling, and clinical investigation are particularly welcomed, provided they demonstrate clear relevance to cellular immunology and tissue engineering.

✦ Article Relevance Criteria

Manuscripts submitted to JCITE should:

• Present original data, concepts, or analyses
• Demonstrate clear relevance to immune-cell-tissue interactions
• Employ scientifically sound and reproducible methodologies
• Contribute meaningful insights to regenerative or immunological sciences

Purely descriptive studies without mechanistic or translational relevance may be considered outside the journal’s scope.

✦ Research Impact and Future Direction

By publishing research that integrates immune principles into tissue engineering strategies, JCITE aims to influence future therapeutic design, improve long-term clinical outcomes, and support the evolution of regenerative medicine into a more immune-aware discipline.

The journal welcomes global contributions and aspires to become a trusted reference for researchers shaping the future of cellular immunology–driven tissue engineering.